Lab 6-Meghan Wright Exercise 1: Part 1: 1. 6 x 10^24 2. 3.45998 x 10^10 3. 1.256 x 10 4. 3.456789 x 10^-1 5. 3.32 x 10^-8 6. 1.23456789 x 10^-31 7. 6 x 10^12 Part 2: 1. 300000 2. 0.000000244 3. 602000000000000000000000 4. 0.000000000000000000000000000000000662 5. 15000000000 5. 0.144 Exercise 2: ||
A
B
i
|| A
AA
AB
Ai
|| B
AB
BB
Bi
|| i
Ai
Bi
ii
Genotype probability
AA = 1/9 (A Blood type)
AB = 2/9 (AB Blood type)
Ai = 2/9 (A Blood type)
BB = 1/9 (B Blood type)
Bi = 2/9 (B Blood type)
ii =1/9 (O blood type) Phenotype probability
A = 3/9
AB = 2/9
B = 3/9
O =1/9 ACTUAL PHENOTYPE FREQUENCY (from website)
A = 31%
AB = 5% B = 14%
O = 49% - 49% of the population is blood type O, 31% are Blood type A, 14% are Blood type B and 5% are blood type AB. This suggests that Blood type O is the most common blood type and AB is the rarest Blood type. This distribution can be attributed to the fact that genes determine blood type and some ethnic groups have certain blood types which could explain the large O type distribution given that the western population is larger and more likely to have O type blood while smaller Ethnic populations have the more rare types of blood. Exercise 3: Case #1: -Pop1 cannot be excluded [.43x.57] x [(.55 x .46)^2] x [(.48x.52)^2] x [(.4)^2 x .6] x [(.56)^2 x .15] = .2451 x .064009 x .06230016 x .096 x .04704 = .000004413 4.413 x 10^-6% -Pop 2 is excluded at GYPA Case #2: -Pop 1 cannot be excluded [(.57)^2 x .43] x [(.46)^2 x .55] x [(.48)^2 x .52] x [(.4)^2 x .6] x [(.56)^2 x .15] .139707 x .11638 x .119808 x .096 x .04704 = .000008796 8.796 x 10^-6% -Pop 2 cannot be excluded [(.43)^2 X .57] x [(.46)^2] x [(.48)^2 x .52] x [(.4)^2 x .6] x [(.56)^2 x .29 x .15] .105393 x .2116 x .119808 x .096 x .0136416 = .000003499 3.499 x 10^-6% Case #3: -Pop 1 cannot be excluded [.43 x .57] x [(.55)^2 x (.46)^2] x [(.48)^2 x (.52)^2] x [(.4)^2 x .6] x [(.56)^2 x .15] .2451 x .064009 x .06230016 x .096 x .04704 = .000004413 4.413 x 10^-6% - Pop 2 cannot be excluded [.43^2] x [(.55)^2 x .46] x [.48x .52 x .006] x [.6 x .4] x [(.15)^2 x .29 x .56] .1849 x .13915 x .0014976 x .24 x .003654 = .000000033 3.3 x 10^-8% Case #4: -Pop 1 cannot be excluded [.43^2] x [(.46)^2 x .55] x [(.48)^2 x .52] x [(.4)^2 x .6] x [(.56)^2 x .15] .1849 x .11638 x .119808 x .096 x .04704 = .0000119 1.19 x 10^-5% -Pop 2 is excluded at GYPA Part 2:
(picture of Dot Blot could not be converted to .jpg from lab window)
[2(.43 X .57)] x[.46^2] x [2(.48 x .006)] x [.6^2] x [2(.29 x .15)] .4902 x .2116 x .00576 x .36 x .087 = .000018712 1.8712 x 10^-5 %
Exercise 1:
Part 1:
1. 6 x 10^24
2. 3.45998 x 10^10
3. 1.256 x 10
4. 3.456789 x 10^-1
5. 3.32 x 10^-8
6. 1.23456789 x 10^-31
7. 6 x 10^12
Part 2:
1. 300000
2. 0.000000244
3. 602000000000000000000000
4. 0.000000000000000000000000000000000662
5. 15000000000
5. 0.144
Exercise 2:
||
A
B
i
Genotype probability
AA = 1/9 (A Blood type)
AB = 2/9 (AB Blood type)
Ai = 2/9 (A Blood type)
BB = 1/9 (B Blood type)
Bi = 2/9 (B Blood type)
ii =1/9 (O blood type)
Phenotype probability
A = 3/9
AB = 2/9
B = 3/9
O =1/9
ACTUAL PHENOTYPE FREQUENCY (from website)
A = 31%
AB = 5%
B = 14%
O = 49%
- 49% of the population is blood type O, 31% are Blood type A, 14% are Blood type B and 5% are blood type AB. This suggests that Blood type O is the most common blood type and AB is the rarest Blood type. This distribution can be attributed to the fact that genes determine blood type and some ethnic groups have certain blood types which could explain the large O type distribution given that the western population is larger and more likely to have O type blood while smaller Ethnic populations have the more rare types of blood.
Exercise 3:
Case #1:
-Pop1 cannot be excluded
[.43x.57] x [(.55 x .46)^2] x [(.48x.52)^2] x [(.4)^2 x .6] x [(.56)^2 x .15] =
.2451 x .064009 x .06230016 x .096 x .04704 = .000004413
4.413 x 10^-6%
-Pop 2 is excluded at GYPA
Case #2:
-Pop 1 cannot be excluded
[(.57)^2 x .43] x [(.46)^2 x .55] x [(.48)^2 x .52] x [(.4)^2 x .6] x [(.56)^2 x .15]
.139707 x .11638 x .119808 x .096 x .04704 = .000008796
8.796 x 10^-6%
-Pop 2 cannot be excluded
[(.43)^2 X .57] x [(.46)^2] x [(.48)^2 x .52] x [(.4)^2 x .6] x [(.56)^2 x .29 x .15]
.105393 x .2116 x .119808 x .096 x .0136416 = .000003499
3.499 x 10^-6%
Case #3:
-Pop 1 cannot be excluded
[.43 x .57] x [(.55)^2 x (.46)^2] x [(.48)^2 x (.52)^2] x [(.4)^2 x .6] x [(.56)^2 x .15]
.2451 x .064009 x .06230016 x .096 x .04704 = .000004413
4.413 x 10^-6%
- Pop 2 cannot be excluded
[.43^2] x [(.55)^2 x .46] x [.48x .52 x .006] x [.6 x .4] x [(.15)^2 x .29 x .56]
.1849 x .13915 x .0014976 x .24 x .003654 = .000000033
3.3 x 10^-8%
Case #4:
-Pop 1 cannot be excluded
[.43^2] x [(.46)^2 x .55] x [(.48)^2 x .52] x [(.4)^2 x .6] x [(.56)^2 x .15]
.1849 x .11638 x .119808 x .096 x .04704 = .0000119
1.19 x 10^-5%
-Pop 2 is excluded at GYPA
Part 2:
(picture of Dot Blot could not be converted to .jpg from lab window)
[2(.43 X .57)] x[.46^2] x [2(.48 x .006)] x [.6^2] x [2(.29 x .15)]
.4902 x .2116 x .00576 x .36 x .087 = .000018712
1.8712 x 10^-5 %